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Histopathology and Immunohistochemistry assessments of acute experimental infection by Brucella melitensis in bucks


Citation

Nurrul Shaqinah Nasruddin and Mazlina Mazlan and Mohd Zamri Saad and Hazilawati Hamzah and Jasni Sabri (2014) Histopathology and Immunohistochemistry assessments of acute experimental infection by Brucella melitensis in bucks. Open Journal of Pathology, 4 (2). pp. 48-57. ISSN 2164-6783

Abstract

Background: Brucellosis in male goats is characterized by arthritis, orchitis and epididymitis, which may induce infertility. Nevertheless, these lesions were categorized as chronic while acute lesions had not been described. This study investigates the histopathological and immuno histochemistry reactions in organs of bucks acutely infected by Brucella melitensis. Results: Only testis and prepuce of acutely infected bucks showed significantly severe histological lesions. Other internal organs had mild to moderate lesions. However, positive immunohistochemistry stainings were observed in organs except the bulbourethral gland. There was a significant positive correlation between the distribution of B. melitensis and IHC intensity but no significant correlation between the IHC intensity and histopathology lesions. Conclusion: The results indicate that acute brucellosis did not lead to clinical presentation, although B. melitensis was well distributed in various organs of bucks.

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Additional Metadata

Item Type: Non-Indexed Article
Collection Type: Institution
Date: April 2014
Journal or Publication Title: Open Journal of Pathology
ISSN: 2164-6783
Uncontrolled Keywords: Histopathology: Immunohistochemistry: Brucella melitensis: Bucks
Faculty/Centre/Office: Faculty of Veterinary Medicine
URI: http://discol.umk.edu.my/id/eprint/8420
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