The lipstick that made up of natural colorant is not widely being commercialized like synthetic colorant. So, the study was aimed at measuring the effect of using natural colorant to, the formulated lipstick in term of surface anomalies by comparing the synthetic colorant of lipstick which is based on the formation of crystallization mould growth, arid aging stability. The natural colorant was extracted using red dragon fruit, butterfly pea flower and pandan leaves to obtain the betacyanin, anthocyanin and chlorophyll colour pigment. The formulated lipstick of synthetic colorant was using the red No, 40, blue FCF No.1 and green No.3. Both formulated lipsticks were stored in different temperature at 4°C, ambient temperature and 37°C in a week for observation, The results of the study showed that there are no sign of phenomenon regarding surface anomalies and aging stability for both synthetic and natural formulated lipstick but the differences is the natural colorant does not mixed well with the ingredients of lipstick such as beeswax, castor oil and glycerine which then the colourless lipstick is obtained together with the formation of spots on the surface of formulated lipstick. The results obtained showed that using synthetic colorant is more significance In making formulated lipstick.