Paraburkholderia kururiensis UMK-PPS6 is one of the PGPB strain bacteria that can help the growth of agricultural trees for the production of agricultural products. It has been identified for its ability to establish a symbiotic relationship with plants, especially in the Rhizosphere in soil areas directly affected by root secretions. Through this study, the ability of Paraburkholderia kururiensis UMK-PPS6 to help the growth of paddy plants based on the parameters of chlorophyll content, growing leaf length and moisture content was explored. Then, this research investigates the antimicrobial activity of Paraburkholderia kururiensis UMK-PPS6 and explores its potential effects on improving salinity stress tolerance in plants. Paddy plants inoculated with Paraburkholderia kururiensis UMK-PPS6 were subjected to different salinity levels (50mM, 100mM and 150mM), and their growth and physiological responses were carefully analyzed. In the antimicrobial activity segment, research investigated the inhibitory effect of Paraburkholderia kururiensis UMK-PPS6 on both gram-positive (Bacillus subtilis) and gram-negative (Escherichia coli) bacteria. The experimental setup involves culturing the bacteria and evaluating its effect on bacterial growth, providing insight into its potential as an antimicrobial agent. Overall, this investigation contributes to the understanding of Paraburkholderia kururiensis UMK-PPS6 as a multifaceted microorganism with promising applications in antimicrobial strategies, biocontrol practices, and improving plant stress tolerance. These findings offer valuable insights into the potential use of these bacteria for sustainable and resilient agricultural practices.