The Social Entrepreneurship is science that combines some knowledge like Culture, Geography, Business, Psychology, Anthropology, Engineering, Agroculture, and so on. Social Entrepreneurship (SE) is a program that bridges between theory and its application in society. The main goal of this program does improve the welfare of village community life, including overcoming the problem of poverty that often occurred in the village. This paper describes the experience of running and explains to concept of social entrepreneurship programme in Malaysia conducted by the Universiti Malaysia Kelantan (UMK) and cooperation with St. Gallen University and Institute Technology Bandung. The first SE programme, this programme was followed by 18 international participants from Switzerland, Singapore, Brunei, Thailand, Vietnam, and 49 UMK students. The program had been implemented in seven districts of Tumpat as: Village Tujuh (product: free range Chicken), Village Tujuh Masjid (product: cattle and goat), Village Belukar Neting (product: noni Juice), Village Pak Kerau Hilir (product: catfish), Village Pak Kerau Hulu (product: Akok and Batek), Village Sungai Tapang (product: Mushroom), and Village Tujuh Tengah/ Pos Banjar (product: chillies). There are seven projects and after the program starts, conducted follow-up to ensure the success of a business plan that has been made. From seven programmes, four programmes was failure, two programmes were stable, and one programme was being successful. The second SE programme was followed by 17 UMK students, and it was run in Village Pak Kerau Hilir (product: catfish), Village Pak Kerau Hulu (product: Akok and keropok), Village Tujuh Tengah/ Pos Banjar (product: chillies), and Village Getting (product: traditional cookies). From 5 projects, it was just 3 projects still run until the end of programme. There is difference procedure between SE I and SE II UMK. The differences include the use of expert in SE II. The program follow up for SE II UMK will soon be implemented to ensure poverty eradication program in the village Sri Tujuh to give significant impact to community there.