Current trends in the preparation of Nanoparticles for drug delivery

The efficiency of a drug depends on target specificity and its solubility.
The non-specificity of the drug molecules not only needs extra doses to treat
diseases but also is associated with adverse drug reactions. Thus, newly engineered
nanoparticles as a vector represent an exciting example which has shifted the
paradigm from conventional therapies such as surgery, chemotherapy, and radiation
to the novel drug delivery system. Among the nanocarriers developed so far, silica
and gold nanoparticles have emerged as potential candidates who can deliver different
drug molecules at target sites in a controllable and sustainable approach. In
the present era, drugs released and delivered by engineered nanoparticles have
attracted enough attention because of the prospects in cancer therapy, in particular,
and in the treatment of other ailments. The fundamental properties of nanoparticles
in drug loading, releasing, and biochemical competency can be altered by means of
suitable conjugation with appropriate coatings or external magnetic fields.
Therefore, this book chapter is focused on preparation, development, and application
of very recently reported silica and gold nanoparticle system as a drug
delivery cargo.