A comparative bio-efficacy test of aerosol insecticides with three todiffebrerendt formulations adult of Aedes athopictus mosquitoes in a 40m3 squarebo sizedrY room rmulations containing synthetic pyrethroids were evaluated against lara conditions. The tested aerosol insecticides are commercially sold in the market as a i household insecticide product. The insecticidal efficacy test was based in accordance with the WHO guidelines for efficacy testing of household insecticide product (WHO/HTM/NTDPES/2009.3) and WHO guidelines for safe and effective use of household insecticide products (WHO/CDS/WHOPES/99.1). The dosage mentioned on the label of each aerosol was used in the experiment. Tested aerosol insecticide formulations were coded as (A) Prallethrin 0.090% w/w + d-phenothrin 0.050%w/w, (B) d-transallethrin (72/25) 0.126% w/w + d-phenothrin 0.050%w/w, and (C) transfluthrin 0.040%w/w + cyfluthrin 0.025%w/w. Eight cages, each with 10 mosquitoes were placed in different places of the room. Test mosquitoes were observed for knockdown at 5, 10, 15 and 20 minutes of exposure after applying the aerosol. The mortality rate was determined after 24 hours of holding period. The results showed the highest knockdown and mortality obtained from the aerosol formulation C, containing (transfluthrin 0.040%w/w + cyfluthrin 0.025%w/w), while the lowest knockdown and mortality was found in the aerosol formulation B, containing (d-transallethrin (72/25) 0.126% w/w + d-phenothrin 0.050%w/w) which is significantly important. The average mortality rate after 24 hours for aerosol A is 97.77% follows by aerosol B with 60.83% and aerosol C with the highest mortality rate at 100%. From the results, it can be concluded that the efficacy of different formulation of aerosol which was coded as A. B, and C were acceptable with C being the most effective formulation. In order to implement effective and sustainable vector control measures, there is an urgent need to determine the susceptible level of mosquito populations periodically to insecticides that are commonly used for mosquito control in Malaysia. This study is important as it measures the bio efficacy of synthetic pyrethroid insecticides against Aedes albopictus. This study would be useful while planning use of these insecticides for the control of mosquito vectors and could help public health services to design more effective vector control lomeasures.