Biosynthesis of Silver Nanoparticles of Swietenia macrophylla and evaluation of its antidiabetic and antioxidant activity

The green synthesis of silver nanoparticles using various plant extracts had been a great attention for researchers as it is simple, inexpensive and eco-friendly method. In the present study, silver nanoparticles (AgNPs) were synthesized from Swietenia macrophylla seed extract. The silver nanoparticles produced by the S.macrophylla seed extract were characterized by different techniques including UV-Vis spectroscopy, X-Ray diffraction, Scanning electron microscopy (SEM) and Fourier transform infrared (FTIR) spectroscopy. The AgNPs formation was confirmed by UV-Vis spectroscopy via the colour conversion due to the surface plasma resonance band at 382 nm. AgNPs characterization of X-Ray diffraction (XRD) revealed their crystalline nature and their average size of nanoparticles was 29 nm as determined by using Scherrer's equation. Fourier transform infrared (FTIR) spectroscopy affirmed the role of S.macrophylla extract as a reducing capping agent of silver ions. While, scanning electron microscope (SEM) results indicated that AgNPs were predominantly irregular in shape with small percentage of crystalline form. The synthesized AgNPs of S.macropylla seed extract was found with higher antioxidant activity when compared to seed extract. While, the seed extract revealed higher antidiabetic activity than the synthesized AgNPs of S.macrophylla.