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Development of Potential Antimicrobial Cream Incorporating with Cassia senna Infused Oil


Nurul Atikah Mohamad Radzi (2019) Development of Potential Antimicrobial Cream Incorporating with Cassia senna Infused Oil. Final Year Project thesis, Universiti Malaysia Kelantan. (Submitted)


Cassia senna (Fabaceae) which commonly known as gelenggang is used to cure the skin diseases by applying directly to the damaged skins. The facts that the C. senna has the anti-microbial properties that kills or inhibit the growth of microorganisms draws many researchers to study this plant. Thus, this study aims to evaluate the quality of the developed cream using infused oil of C. senna leaves in terms of physicochemical, stability, antimicrobial and finally establish sensory evaluation. The essential oil of C. senna leaves was infused using olive oil using low heating technique and incorporated in a cream. The cream when mixed with infused oil of C. senna and the petroleum jelly (Vaseline) shows the suitable pH value for the skin of 5. The developed cream should have moderate quality attributes in terms which are accepted aroma, colour, and texture in terms of its physicochemical properties. The developed cream also found to be stable at 25 ̊C for 3 weeks with distinct changes. An antimicrobial activity was conducted to identify the potential of the cream in inhibiting Escherichia coli and Staphylococcus aureus using disk diffusion method. The developed cream was found to significance (P<0.05) inhibiting the two tested bacteria. Finally, a sensory evaluation conducted using 30 amateur evaluators showed no irritation and good acceptance of the developed cream. From the above mentioned findings, it show that the developed cream incorporated with C. senna infused oil would be further analysed and have a potential to
be commercialized as another alternative for those who prefer another alternative for those who prefer natural based antimicrobial cream with mild effects.

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Additional Metadata

Item Type: Undergraduate Final Project Report
Collection Type: Final Year Project
Date: 2019
Number of Pages: 83
Call Number: SBP 2019/027
Supervisor: Dr. Ikarastika Rahayu Binti Abdul Wahab
Programme: Bachelor of Applied Science (Product Development Technology)
Institution: Universiti Malaysia Kelantan
Faculty/Centre/Office: Faculty of Agro - Based Industry
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