The role of women in the development of the human capital contribution cannot be denied. This can be seen from the position of women in key positions in critical sectors, including the academic sector. The Higher Education Institutions are an important sector where it is used to educate young students and provide them with quality in the field work. Thus, in ensuring the best quality of teaching is important to ensure that the staff also can achieve a balance between work and family. The workload is one of the factors that could affect the balance of work and family. Therefore, it is the workload is an effort that should be dealt with by the management in ensuring the work performed and the work environment can be achieved by each employee. However, the tremendous pressure by women working in this great responsibility in the workplace that affect their quality time. Imbalance of work life and job performance than it would contribute to work-life balance. With the uncertainty in terms of the workload given to female lecturers in Polytechnic Kota Bharu, it is everyone's guess how it will affect their work-life balance. The main objective of this study is to see the effect of workload and job satisfaction in the relationship to work life balance among women lecturer at the Polytechnic Kota Bharu. This study is a qualitative study. Data was collected using the interview methods through purposive and convenience sampling. Analysis the data is using the inductive research approach. Analysis of the data shows that workloads are significantly correlated with work life balance but in moderate. Job satisfaction factors also showed a significant correlation in work life balance. However, in determining the work life balance, found that be more influenced by factors of job satisfaction compared to the workload. It means that workers can still handle the workload and balance it in their life as long as there is a job satisfaction in their career. In conclusion, suggestions are proposed for their management in order to help professional women be able to optimize their work capacity while at the same time achieve a balanced work and family life.