Invitro evaluation of graphene oxide on cell culture growth

The skin serves as a critical barrier, preventing hazardous foreign matter from entering the body. Due to this significance, graphene oxide has been used to regenerate skin via wound dressings or electronic skin monitoring. Wound dressings such as electrospun mats, hydrogels, and sponges, are the most effective way to accelerate wound healing, thus, graphene oxide has been incorporated into these types of dressing. Graphene Oxide has been studied to be used in hemorrhage control measures used in accident cases involving hemorrhage and uncontrolled bleeding and graphene oxide can create artificial extracellular matrices for tissue remodeling. It was mentioned that the integration of graphene-based flakes could support cellular proliferation leading to skin regeneration, thus providing wound healing. This research aimed to determine the concentration of graphene oxide that provides cell growth and the concentration of graphene oxide that causes toxicity cell growth in Vero cells. Based on the results from the determination of confluency cells on different types of concentrations of graphene oxide, the number of Vero cells increased parallel to the increase of the concentration of the graphene oxide.
Keywords: Graphene Oxide, cell growth, tissue engineering, cytotoxicity, Vero cells