Therapeutic effect of commercial probiotic lactobacillus on avian colibacillosis

An abstract of the research paper presented to the Faculty of Veterinary Medicine, Universiti Malaysia Kelantan, in partial requirement for the course DVT 5436 – Research Project Avian colibacillosis caused by Escherichia coli is one of the most common diseases in the poultry industry, affecting poultry growth and development. The continued use of antimicrobial medications as treatment for avian colibacillosis has promoted the emergence of antimicrobial resistances toward E. coli. This study investigated the therapeutic effect of probiotic lactobacillus against Escherichia coli isolated from avian colibacillosis. Thus, probiotics were prepared and tested to check their viability and ability of the probiotic against the E. coli. The probiotic lactobacillus was successfully prepared in this study by providing good nutrients and a medium for the lactobacillus bacteria to grow and replicate. The prepared probiotics have low pH values, which indicates low pH values help the lactobacillus withstand an acidic environment like the stomach. The curd formation of probiotic milk test suggested that the lactobacillus were present and viable. The colonization test revealed the probiotic lactobacillus able to colonize the agar and occupied most of the spaces against the E. coli. Moreover, lower concentrations of the probiotic were able to produce a sufficient colonization zone and suppressed the E. coli colonization on the agar. In conclusion, the prepared probiotics in this study had a therapeutic effect against the E. coli and the potential for future commercialization to prevent and treat avian colibacillosis.
Keywords: Avian Colibacillosis, Antimicrobial Resistance, Probiotic, Colonization Test